Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

Search Results - michael+gordon+joyce

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SERINC5 Monoclonal Antibodies - (HJF 525-18)
Serine incorporator 5 (SERINC5), is a host cell protein that has been shown to potently reduce HIV-1 infectivity. However, studies related to SERINC5 protein have been challenging due the dearth of high-quality SERINC5-specific monoclonal antibodies (mAbs). Researchers at the Walter Reed Army Institute of Research (WRAIR) and the Henry M. Jackson Foundation...
Published: 10/17/2024   |   Updated: 3/23/2023   |   Inventor(s): Victoria Polonis, Michael Gordon Joyce, Sebastian Molar, Lindsay Wieczorek, Syna Gift
Keywords(s): Monoclonal Antibodies
Category(s): Research Tool, Potential Therapeutic
Potent ZIKV and DENV neutralizing antibodies induced by ZPIV vaccination - (HJF 508-18)
Researchers at The Henry M. Jackson Foundation (HJF), The Beth Israel Deaconess Medical Center (BIDMC), the Armed Forces Research Institute of Medical Sciences (AFRIMS), and the Walter Reed Army Institute of Research (WRAIR) have identified several monoclonal antibodies (mAbs) with a wide-range of capabilities to precisely neutralize Zika virus (ZIKV)...
Published: 10/17/2024   |   Updated: 1/27/2023   |   Inventor(s): Shelly Krebs, Vincent Dussupt, Gina Donofrio, Kayvon Modjarrad, Nelson Michael, Dan Barouch, Michael Gordon Joyce, Kathryn Stephenson, Rajeshwer Sankhala
Keywords(s):  
Category(s): Diagnostics, Therapeutic, Vaccine
Vaccines against SARS-COV-2 and other Coronaviruses - (HJF 569-20 & HJF 635-22)
Researchers at HJF and the Walter Reed Army Institute of Research (WRAIR) have developed novel vaccines comprised of fusion proteins; Ferritin nanoparticle and antigenic coronavirus peptide(s). These fusion proteins generate simultaneous protective neutralizing immune responses against coronaviruses and their variants. Applications and Advantages Innovation...
Published: 12/12/2024   |   Updated: 1/25/2023   |   Inventor(s): Kayvon Modjarrad, Michael Gordon Joyce
Keywords(s): Coronavirus, COVID-19, Nano-particle, SARS-CoV-2, Self-Assembly, Vaccines, Variants
Category(s): Diagnostics, Therapeutic
Shark Antibodies and Shark-Derived Binding Domains Specific for the SARS-CoV-2 Coronavirus - (HJF 581-20)
HJF scientists have developed a series of single variable domain antibodies (nanobodies or VNARs, derived from nurse sharks) specifically targeting SARS-CoV-2 and other betacoronaviruses, thus providing unique therapeutics and diagnostics for COVID-19 and possibly other betacoronavirus infections. Applications and Advantages Fully sequenced, grafted...
Published: 10/17/2024   |   Updated: 5/20/2022   |   Inventor(s): Michael Gordon Joyce, Kayvon Modjarrad, Helen Dooley
Keywords(s): Antibody, Coronavirus, COVID-19, Diagnostics, Sarbecovirus, SARS-CoV-2, Therapeutics
Category(s): Therapeutic, Diagnostics