Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

Search Results - shelly+krebs

3 Results Sort By:
Immunogens and Vaccine Compositions Against Flavivirus - (HJF 624-22)
HJF researchers have developed a novel recombinant flavivirus immunogen that can induce immunogenicity against multiple flaviviruses, including ZIKV (Zika) and DENV (dengue), without life-threatening antibody-dependent enhancement (ADE) responses. Mice immunized with this recombinant immunogen were protected from lethal ZIKV challenge. Applications...
Published: 12/12/2024   |   Updated: 12/1/2023   |   Inventor(s): Shelly Krebs, Vincent Dussupt
Keywords(s): Dengue, Flavivirus, Immunogen, Vaccines, Zika
Category(s): Diagnostics, Therapeutic
Potent ZIKV and DENV neutralizing antibodies induced by ZPIV vaccination - (HJF 508-18)
Researchers at The Henry M. Jackson Foundation (HJF), The Beth Israel Deaconess Medical Center (BIDMC), the Armed Forces Research Institute of Medical Sciences (AFRIMS), and the Walter Reed Army Institute of Research (WRAIR) have identified several monoclonal antibodies (mAbs) with a wide-range of capabilities to precisely neutralize Zika virus (ZIKV)...
Published: 10/17/2024   |   Updated: 1/27/2023   |   Inventor(s): Shelly Krebs, Vincent Dussupt, Gina Donofrio, Kayvon Modjarrad, Nelson Michael, Dan Barouch, Michael Gordon Joyce, Kathryn Stephenson, Rajeshwer Sankhala
Keywords(s):  
Category(s): Diagnostics, Therapeutic, Vaccine
Monoclonal Antibodies Against Coronavirus and Their Uses - (HJF 595-21)
Researchers at Henry M. Jackson Foundation for Advancement of Military Medicine (HJF) and Walter Reed Army Institute of Research (WRAIR) have discovered new human and recombinant monoclonal antibodies (mAbs) that show broad cross reactivity among coronavirus variants with potential applications in diagnostics and therapeutics for coronavirus. Applications...
Published: 10/17/2024   |   Updated: 1/24/2023   |   Inventor(s): Shelly Krebs, Kayvon Modjarrad, Nelson Michael, Vincent Dussupt, Gina Donofrio, Samantha Townsley
Keywords(s): Coronavirus, COVID-19, Cross-Reactivity, Monoclonal Antibodies, Respiratory, SARS, SARS-CoV-2, Spike Proteins, Vaccines, Variants
Category(s): Diagnostics, Therapeutic