Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

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ETV1 Monoclonal Antibodies - (HJF 641-23)
ETV1 is a protein of Erythroblast Transformation Specific (ETS) family of transcription factors. Dysregulation of ETV-1 has been observed in many malignancies including, gastrointestinal stromal (GIS), prostatic tumors, and in triple-negative breast cancer. Researchers at Henry M. Jackson Foundation (HJF) and Uniformed Services University for Health...
Published: 10/17/2024   |   Updated: 4/5/2023   |   Inventor(s): Shyh-Han Tan, Albert Dobi, Shiv Srivastava
Keywords(s): ERG, Monoclonal Antibodies, Prostate Cancer
Category(s): Diagnostics, Research Tool, Therapeutic
SERINC5 Monoclonal Antibodies - (HJF 525-18)
Serine incorporator 5 (SERINC5), is a host cell protein that has been shown to potently reduce HIV-1 infectivity. However, studies related to SERINC5 protein have been challenging due the dearth of high-quality SERINC5-specific monoclonal antibodies (mAbs). Researchers at the Walter Reed Army Institute of Research (WRAIR) and the Henry M. Jackson Foundation...
Published: 10/17/2024   |   Updated: 3/23/2023   |   Inventor(s): Victoria Polonis, Michael Gordon Joyce, Sebastian Molar, Lindsay Wieczorek, Syna Gift
Keywords(s): Monoclonal Antibodies
Category(s): Research Tool, Potential Therapeutic
Fully Human Skin Substitute with True Human Hair Follicle Neogenesis - (HJF 220-09)
Human skin substitutes available today have varied compositions but generally comprise a nonliving collagen matrix and different combinations of keratinocytes and fibroblasts. However, currently available skin substitutes cannot perform all the functions of normal skin. For example, hair follicle (HF) neogenesis is not observed using any currently available...
Published: 5/6/2024   |   Updated: 6/28/2022   |   Inventor(s): Thomas Darling, Shaowei Li, Rajesh Thangapazham
Keywords(s): Hair Follicle Neogenesis, Human Skin Substitute
Category(s): Research Tool, Therapeutic
Rotifer Culture Controller and Algae Doser for Zebrafish Husbandry - (HJF 563-20)
The zebrafish (Danio rerio) has become a popular model organism in biomedical research. Multiple advantages of using this species in biomedicine include high physiological and genetic homology to mammals, external fertilization, rapid development, transparency of embryos and larvae, ease of genetic and other experimental manipulations, as well as cost-...
Published: 5/6/2024   |   Updated: 6/27/2022   |   Inventor(s): Benjamin Garcia
Keywords(s): Algae, Culture, Husbandry, Rotifer, Zebra Fish
Category(s): Research Tool
Compounds to Reverse Organophosphorus Nerve Agent Poisoning - HJF Tech ID: HJF 429-16
Organophosphates (OP) are widely used as insecticides (both agricultural and household) and are also a major component of nerve agent weapons. OP exposure may occur through inhalation, ingestion, or dermal contact. Symptoms include increased saliva and tear production, diarrhea, nausea, vomiting, small pupils, sweating, muscle tremors, and confusion....
Published: 3/12/2024   |   Updated: 3/8/2022   |   Inventor(s): Ilja Khavrutskii, Sven Anders Wallqvist
Keywords(s): Acetylcholinesterase, Counterterrorism, Organophosphate, Pesticide
Category(s): Therapeutic, Research Tool