Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

Search Results - organophosphate

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Novel Drug Combination Treatment for Nerve Agent and Organophosphate Poisoning in Children - (HJF 447-16)
Organophosphates (OP) which include pesticides and nerve agents are a common source of poisoning with approximately 3 million worldwide exposures each year and around 300,000 resulting deaths. Researchers at USUHS have developed a novel treatment formulation to treat CNS symptoms including status epilepticus (SE), with a special emphasis on pediatric...
Published: 5/6/2024   |   Updated: 3/8/2022   |   Inventor(s): Maria F.M. Braga, Vassiliki Aroniadou-Anderjaska
Keywords(s): CNS, Nerve Agent, Organophosphate, Pediatric, Poison, Seizure, Status Epilepticus
Category(s): Therapeutic
Compounds to Reverse Organophosphorus Nerve Agent Poisoning - HJF Tech ID: HJF 429-16
Organophosphates (OP) are widely used as insecticides (both agricultural and household) and are also a major component of nerve agent weapons. OP exposure may occur through inhalation, ingestion, or dermal contact. Symptoms include increased saliva and tear production, diarrhea, nausea, vomiting, small pupils, sweating, muscle tremors, and confusion....
Published: 3/12/2024   |   Updated: 3/8/2022   |   Inventor(s): Ilja Khavrutskii, Sven Anders Wallqvist
Keywords(s): Acetylcholinesterase, Counterterrorism, Organophosphate, Pesticide
Category(s): Therapeutic, Research Tool