Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

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SETBP1 and XPO1 inhibitors for the treatment of Sickle cell disease and β- Thalassemia - (HJF 547-19)
Researchers at the Uniformed Services University for the Health Sciences (USU) and HJF have developed small molecules that can be used to reactivate embryonic and fetal hemoglobin expression for use as therapeutics for sickle-cell disease (SCD) and β-Thalassemia. Applications and Advantages Effective inducing of embryonic and fetal hemoglobin...
Published: 12/12/2024   |   Updated: 1/25/2023   |   Inventor(s): Yang (Dennis) Du, Nhu Nguyen, Kristbjorn Gudmundsson
Keywords(s): Embryonic, Fetal, Hemoglobin, SETBP1, Sickle Cell Disease, XP01, β-thalassemia
Category(s): Therapeutic